Imaging differentiates progressive supranuclear palsy from Parkinson disease
نویسندگان
چکیده
منابع مشابه
Parkinson disease and progressive supranuclear palsy: protein expression in skin
OBJECTIVE This study characterizes the expression of tau (p-tau) and α-synuclein (α-syn) by immunohistochemistry in the skin of three different populations: healthy control (HC), Parkinson disease (PD), and progressive supranuclear paralysis (PSP) subjects, with the purpose of finding a biomarker that could differentiate between subjects with PD and PSP. MATERIAL AND METHODS We evaluated the ...
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Clinical Features of Progressive Supranuclear Palsy Progressive supranuclear palsy (PSP) is a neurodegenerative disorder characterised by parkinsonism, supranuclear ophthalmoplegia, dysphagia and cognitive dysfunction. The National Institute of Neurological Disorders and Stroke (NINDS) PSP criteria are widely used for clinical diagnosis. However, the clinical phenotypes of pathologically confir...
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Progressive supranuclear palsy (PSP) is characterized by slowness, rigidity, bradykinesia, repeated falls, downgaze limitation and dementia. Midbrain atrophy on magnetic resonance imaging is highly suggestive of PSP and is described as "hummingbird sign". This sign is very helpful in differentiating PSP patients from those with Parkinson's disease.We hereby report a 72-year-old female case of P...
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ژورنال
عنوان ژورنال: Nature Reviews Neurology
سال: 2011
ISSN: 1759-4758,1759-4766
DOI: 10.1038/nrneurol.2011.31